John Scane was born in Los Angeles in 1967. Spending the first year of life as a foster child Scane was later adopted by his foster parents and raised in the small town of Glendora in Southern California.

After attending California State University Long Beach, Scane became active in the Los Angeles art scene. Trained primarily as a painter Scane has expanded his skills to include photography, design, woodworking and sculpture. For 15 years he owned his own woodworking business where he designed and built many custom furniture pieces. He has exhibited his art nationally and internationally, received a generous amount of press and has his work in many private collections. In 2003 he co-founded the artist group Pharmaka that is based in Los Angeles.